CYP7B1 antibody
Product Specifications
Background
Oxysterol 7alpha-hydroxylase that mediates formation of 7-alpha,25-dihydroxycholesterol(7-alpha,25-OHC) from 25-hydroxycholesterol(PubMed:10588945). Plays a key role in cell positioning and movement in lymphoid tissues: 7-alpha,25-dihydroxycholesterol(7-alpha,25-OHC) acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells(By similarity).
Synonyms
Cytochrome P450 7B1|24-hydroxycholesterol 7-alpha-hydroxylase|25/26-hydroxycholesterol 7-alpha-hydroxylase|3-hydroxysteroid 7-alpha hydroxylase|Oxysterol 7-alpha-hydroxylase|CYP7B1
Gene ID
9420
UniProt
O75881
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
cytochrome P450, family 7, subfamily B, polypeptide 1
Target
CYP7B1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-55 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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