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CYP7B1 antibody

Product Specifications

Background

Oxysterol 7alpha-hydroxylase that mediates formation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) from 25-hydroxycholesterol (PubMed:10588945) . Plays a key role in cell positioning and movement in lymphoid tissues: 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells (By similarity) .

Synonyms

Cytochrome P450 7B1|24-hydroxycholesterol 7-alpha-hydroxylase|25/26-hydroxycholesterol 7-alpha-hydroxylase|3-hydroxysteroid 7-alpha hydroxylase|Oxysterol 7-alpha-hydroxylase|CYP7B1

Gene ID

9420

UniProt

O75881

Host

Rabbit

Reactivity

Human

Immunogen

Cytochrome P450, family 7, subfamily B, polypeptide 1

Target

CYP7B1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Cardiovascular, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

50-55 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IF

Frequently Asked Questions

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