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Phenylsulfamide

Phenylsulfamide (Compound 10) is a human carbonic anhydrase-II (hCA-II) inhibitor with a Kd of 45.50 μM and a Ki of 79.60 μM[1].

Product Specifications

CAS Number

[15959-53-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/phenylsulfamide.html

Solubility

10 mM in DMSO

Smiles

O=S(N)(NC1=CC=CC=C1)=O

Molecular Formula

C6H8N2O2S

Molecular Weight

172.20

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Klinger AL, et al. Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements. J Med Chem. 2006 Jun 15;49 (12) :3496-500.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CA II

Available Sizes

Curated Selection

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