Phenylsulfamide
Phenylsulfamide (Compound 10) is a human carbonic anhydrase-II (hCA-II) inhibitor with a Kd of 45.50 μM and a Ki of 79.60 μM[1].
Product Specifications
CAS Number
15959-53-2
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/phenylsulfamide.html
Solubility
10 mM in DMSO
Smiles
O=S(N)(NC1=CC=CC=C1)=O
Molecular Formula
C6H8N2O2S
Molecular Weight
172.20
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Klinger AL, et al. Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements. J Med Chem. 2006 Jun 15;49 (12) :3496-500.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II
Available Sizes
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