ATX inhibitor 17
Product Specifications
UNSPSC Description
ATX inhibitor 17 is a potent ATX inhibitor with an IC50 of 0.019 μM. ATX inhibitor 17 shows excellent anti-proliferative activities in breast cancer cells[1].
Target Antigen
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/atx-inhibitor-17.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C2=CC(N3CCN(CC3)CCN(C)C)=C(C=C2N1)F)/C(C(F)(F)F)=N/NC4=NC(C5=CC=C(C=C5)F)=C(S4)C#N
Molecular Weight
616.65
References & Citations
[1]Lei H,et al. Structure guided design of potent indole-based ATX inhibitors bearing hydrazone moiety with tumor suppression effects. Eur J Med Chem. 2020 Sep 1;201:112456.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146890/ATX-inhibitor-17-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146890/
Clinical Information
No Development Reported
CAS Number
2750152-64-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
