HDAC-IN-38
Product Specifications
UNSPSC Description
HDAC-IN-38 (compound 13) is a potent HDAC inhibitor. HDAC-IN-38 shows similar micro-molar inhibitory activity toward HDAC1, 2, 3, 5, 6, and 8. HDAC-IN-38 increases cerebral blood flow (CBF), attenuates cognitive impairment, and improves hippocampal atrophy. HDAC-IN-38 also increases the level of histone acetylation (H3K14 or H4K5)[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hdac-in-38.html
Solubility
10 mM in DMSO
Smiles
O=C(NO)/C=C/C1=CC=C(C=C1)CNCCCN2C3=C(CCC4=C2C=C(C=C4)Cl)C=CC=C3
Molecular Weight
461.98
References & Citations
[1]Kaur N, et al. Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment. Eur J Med Chem. 2020 Feb 1;187:111915.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146351/HDAC-IN-38-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146351/
Clinical Information
No Development Reported
CAS Number
2408123-36-2
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Monoclonal Cytokeratin, LMW Antibody (KRTL/4440R) [Janelia Fluor 646]](https://cdn.genprice.uk/genprice/genprice3.png)
NBP3-08422JF646 100 µL
Rabbit Monoclonal Cytokeratin, LMW Antibody (KRTL/4440R) [Janelia Fluor 646]
Ask
View Details 
