P1788
P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor. P1788 induces DNA damage[1].
Product Specifications
CAS Number
[2554623-76-4]
UNSPSC
12352005
Target
Dihydroorotate Dehydrogenase; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/p1788.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2(C3=C1C(N(C=C3)C4CC4)=O)CCCCC2
Molecular Formula
C15H17NO3
Molecular Weight
259.30
References & Citations
[1]Hayek S, et al. Cerpegin-derived furo[3,4-c]pyridine-3,4 (1H,5H) -diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition. Eur J Med Chem. 2020 Jan 15;186:111855.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146317/P1788-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146317/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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