HCAIX/XII-IN-3
HCAIX/XII-IN-3 (compound 6q) is a potent and selective hCAIX and hCAXIIinhibitor with Ki values of >10000, >10000, 66.2, 4.4 nM for hCAI, hCAII, hCAIX and hCAXII, respectively[1].
Product Specifications
CAS Number
2414629-94-8
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcaix-xii-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C)C2=C(O1)C=C(OCC3=NOC(C4=CC=C(C(F)(F)F)C=C4)=N3)C=C2
Molecular Formula
C20H13F3N2O4
Molecular Weight
402.32
References & Citations
[1]Thacker PS, et al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA IX
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PX-SCL0023 1 vial of 2x10^6 cells
Human FAP HEK293T Stable Cell Line
Sign In for Pricing
View Details 
orb54688-01 20 µg
Fish Salmo salar Vertebrate ancient opsin protein
Sign In for Pricing
View Details orb54688-02 100 µg
Fish Salmo salar Vertebrate ancient opsin protein
Sign In for Pricing
View Details