IDO1-IN-20
Hy-146215 is an enzyme that catalyzes the oxidative metabolism of tryptophan. It can immunosuppress tumors in the tumor microenvironment.
Product Specifications
CAS Number
[2415246-15-8]
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ido1-in-20.html
Solubility
10 mM in DMSO
Smiles
NS(=O)(N1CCC[C@H](C1)CNC2=NON=C2/C(NC3=CC(Br)=C(C=C3)F)=N/O)=O
Molecular Formula
C15H19BrFN7O4S
Molecular Weight
492.32
References & Citations
[1]Song X, et al. Design, synthesis, and biological evaluation of 1,2,5-oxadiazole-3-carboximidamide derivatives as novel indoleamine-2,3-dioxygenase 1 inhibitors. Eur J Med Chem. 2020 Mar 1;189:112059.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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