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IDO1-IN-20

Hy-146215 is an enzyme that catalyzes the oxidative metabolism of tryptophan. It can immunosuppress tumors in the tumor microenvironment.

Product Specifications

CAS Number

2415246-15-8

UNSPSC

12352005

Target

Indoleamine 2,3-Dioxygenase (IDO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ido1-in-20.html

Solubility

10 mM in DMSO

Smiles

NS(=O)(N1CCC[C@H](C1)CNC2=NON=C2/C(NC3=CC(Br)=C(C=C3)F)=N/O)=O

Molecular Formula

C15H19BrFN7O4S

Molecular Weight

492.32

References & Citations

[1]Song X, et al. Design, synthesis, and biological evaluation of 1,2,5-oxadiazole-3-carboximidamide derivatives as novel indoleamine-2,3-dioxygenase 1 inhibitors. Eur J Med Chem. 2020 Mar 1;189:112059.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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