Encephalitic alphavirus-IN-1
Product Specifications
UNSPSC Description
Encephalitic alphavirus-IN-1 has antiviral activity for VEEV and EEEV with EC50s of 0.24 μM and 0.16 μM, respectively. Encephalitic alphavirus-IN-1 has robust mouse plasma stability, and no obvious cytotoxicity[1].
Target Antigen
Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/encephalitic-alphavirus-in-1.html
Solubility
10 mM in DMSO
Smiles
[H]C12C(N(CCN2C)C)=NC3=C(C=C(C=C3C(N1C4=CC(F)=C(C=C4)OC)=O)C#N)C5=CC=C(N=C5)C
Molecular Weight
484.52
References & Citations
[1]Ryan MC, et al. Piperazinobenzodiazepinones: New Encephalitic Alphavirus Inhibitors via Ring Expansion of 2-Dichloromethylquinazolinones. ACS Med Chem Lett. 2022;13(4):546-553. Published 2022 Mar 14.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145842/Encephalitic-alphavirus-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145842/
Clinical Information
No Development Reported
Curated Selection
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