Dideoxycytidinene
Dideoxycytidinene (2′,3′-Didehydro-2′,3′-dideoxycytidine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[7481-88-1]
Product Name Alternative
2′,3′-Didehydro-2′,3′-dideoxycytidine
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dideoxycytidinene.html
Purity
98.36
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1C=C[C@H](N2C(N=C(N)C=C2)=O)O1
Molecular Formula
C9H11N3O3
Molecular Weight
209.20
Precautions
H315, H319, H320
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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