KRAS inhibitor-11
KRAS inhibitor-11 (compound 12) is a KRAS inhibitor[1].
Product Specifications
CAS Number
[2761218-40-8]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-inhibitor-11.html
Solubility
10 mM in DMSO
Smiles
CC(C)C[C@H](NC([C@H](CCN1C=C(CCCC(NCC(N2[C@H]3CCC2)=O)=O)N=N1)NC([C@@H](NC3=O)[C@H](CC)C)=O)=O)C(N)=O
Molecular Formula
C29H47N9O6
Molecular Weight
617.74
References & Citations
[1]Fumagalli G, et al. Targeting a Novel KRAS Binding Site: Application of One-Component Stapling of Small (5-6-mer) Peptides. J Med Chem. 2021;64 (23) :17287-17303.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
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