PTP1B-IN-18
PTP1B-IN-18 is an orally active complete mixed type protein tyrosine phosphatase 1B (PTP1B) inhibitor with a Ki of 35.2 μM. PTP1B-IN-18 can be used for type 2 diabetes research[1].
Product Specifications
CAS Number
2848581-84-8
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ptp1b-in-18.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C=C1)C(O)=O)CSC2=NC3=C(N2)C=CC(OC4=CC=C5C=CC=CC5=C4)=C3
Molecular Formula
C26H19N3O4S
Molecular Weight
469.51
References & Citations
[1]Mara Ibeth Campos-Almazán, et al. Design, synthesis, kinetic, molecular dynamics, and hypoglycemic effect characterization of new and potential selective benzimidazole derivatives as Protein Tyrosine Phosphatase 1B inhibitors. Bioorg Med Chem. 2021 Oct 15
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PKSH033176-01 10 µg
Recombinant Human UCHL3/UCH-L3 Protein (His Tag)
Sign In for Pricing
View Details PKSH033176-02 50 µg
Recombinant Human UCHL3/UCH-L3 Protein (His Tag)
Sign In for Pricing
View Details 
