Carbonic anhydrase inhibitor 5
Carbonic anhydrase inhibitor 5 is a potent and selective human carbonic anhydrase (hCA) inhibitor with IC50s of 42.9, 47,6 and 6.7 nM for hCA II, hCA IX and hCA XII, respectively[1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/carbonic-anhydrase-inhibitor-5.html
Solubility
10 mM in DMSO
Smiles
NS(=O)(C1=CC=C(C=C1)CCNC(C2=CC(C3=CC=CC=C3)=NC4=CC=C(C=C42)Cl)=O)=O
Molecular Formula
C24H20ClN3O3S
Molecular Weight
465.95
References & Citations
[1]Swain B, et al. Exploration of 2-phenylquinoline-4-carboxamide linked benzene sulfonamide derivatives as isoform selective inhibitors of transmembrane human carbonic anhydrases. Eur J Med Chem. 2022;234:114247.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II; CA IX; CA XII
Frequently Asked Questions
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