SHR5133
SHR5133 is a highly potent, orally active HBV capsid assembly modulator. SHR5133 displays HBV DNA reduction (EC50=26.6 nM) [1].
Product Specifications
CAS Number
2270943-23-0
UNSPSC
12352005
Target
HBV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/shr5133.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C2CN(C(NC3=CC=C(F)C(C#N)=C3)=O)[C@@H](C)CN2C=N1)N[C@H](C)C(F)(F)F
Molecular Formula
C19H18F4N6O2
Molecular Weight
438.38
References & Citations
[1]Li X, et al. Discovery of SHR5133, a Highly Potent and Novel HBV Capsid Assembly Modulator. ACS Med Chem Lett. 2022;13 (3) :507-512. Published 2022 Feb 17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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