HPK1-IN-27
Product Specifications
UNSPSC Description
HPK1-IN-27 is a potent inhibitor of HPK1. MAP4K1 is also known as hematopoietic progenitor kinase 1 (HPK1). MAP4K1 is a serine/threonine kinase and member of the germinal center kinase family. HPK1-IN-27 has the potential for the research of cancer diseases (extracted from patent WO2019016071A1, compound 38)[1].
Target Antigen
MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpk1-in-27.html
Solubility
10 mM in DMSO
Smiles
OCC1(C)CN=C(NC2=CC(F)=C(OC3=C4C(NC=C4C5=CC=C(OC)C=C5F)=NC=C3)C(F)=C2)OC1
Molecular Weight
512.48
References & Citations
[1]Jeffrey Stuart MOWAT, et al. Substituted pyrrolopyridine-derivatives. Patent WO2019016071A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-143868/HPK1-IN-27-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-143868/
Clinical Information
No Development Reported
CAS Number
2268794-52-9
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6472817-01 0.1 mL
DOK1, NT (Docking Protein 1, Downstream Of Tyrosine Kinase 1, p62(dok), pp62) (MaxLight 405)
Ask
View Details MBS6472817-02 5x 0.1 mL
DOK1, NT (Docking Protein 1, Downstream Of Tyrosine Kinase 1, p62(dok), pp62) (MaxLight 405)
Ask
View Details 