HPK1-IN-27
HPK1-IN-27 is a potent inhibitor of HPK1. MAP4K1 is also known as hematopoietic progenitor kinase 1 (HPK1) . MAP4K1 is a serine/threonine kinase and member of the germinal center kinase family. HPK1-IN-27 has the potential for the research of cancer diseases (extracted from patent WO2019016071A1, compound 38) [1].
Product Specifications
CAS Number
[2268794-52-9]
UNSPSC
12352005
Target
MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpk1-in-27.html
Solubility
10 mM in DMSO
Smiles
OCC1(C)CN=C(NC2=CC(F)=C(OC3=C4C(NC=C4C5=CC=C(OC)C=C5F)=NC=C3)C(F)=C2)OC1
Molecular Formula
C26H23F3N4O4
Molecular Weight
512.48
References & Citations
[1]Jeffrey Stuart MOWAT, et al. Substituted pyrrolopyridine-derivatives. Patent WO2019016071A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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