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Biotin-PEG10-NHS ester

Biotin-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

UNSPSC

12352005

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/biotin-peg10-nhs-ester.html

Purity

98.02

Solubility

10 mM in DMSO

Smiles

O=C(CCCC[C@@H]1SC[C@]([H])(N2)[C@@]1(NC2=O)[H])NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O

Molecular Formula

C37H64N4O16S

Molecular Weight

852.99

References & Citations

[1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-985.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

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