VEGFR-IN-3
VEGFR-IN-3 (compound 3f) is a VEGFR inhibitor. VEGFR-IN-3 inhibits OVCAR-4 and MDA-MB-468 cancer cells growth with IC50s of 0.29 and 0.35 μM, respectively. VEGFR-IN-3 can be used for the research of cancer[1].
Product Specifications
CAS Number
2874264-13-6
UNSPSC
12352005
Target
Apoptosis; VEGFR
Type
Reference compound
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-in-3.html
Solubility
10 mM in DMSO
Smiles
CC(N(C(C1)C2=CC=C(C=C2)OC3=CC=C(C=C3)OC)N=C1C4=CC(OC)=C(OC)C(OC)=C4)=O
Molecular Formula
C27H28N2O6
Molecular Weight
476.52
References & Citations
[1]Hassan RA, et al. Design, synthesis and evaluation of anticancer activity of new pyrazoline derivatives by down-regulation of VEGF: Molecular docking and apoptosis inducing activity. Bioorg Chem. 2022 Jan;118:105487.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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