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HIV-1 inhibitor-12

HIV-1 inhibitor-12 is potent HIV-1 inhibitor. HIV-1 inhibitor-12 inhibits HIV-1 capsid protein polymerization with an IC50 of 9 nM (WO2021104413A1, compound 1-1a) [1].

Product Specifications

UNSPSC

12352005

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hiv-1-inhibitor-12.html

Solubility

10 mM in DMSO

Smiles

O=C(CN(N=C1C(F)(F)F)C2=C1[C@@H](C3)[C@@H]3C2(F)F)N[C@@H](CC4=CC(F)=CC(F)=C4)C5=[C@](C6=C(C(C#CC(C)(S(C)(=O)=O)C)=N5)CCC6)[C@]7=C8C(C(NS(C)(=O)=O)=NN8CC(F)(F)F)=C(C=C7)Cl

Molecular Formula

C42H36ClF10N7O5S2

Molecular Weight

1008.35

References & Citations

[1]Fused pyridine ring derivative, preparation method therefor, and pharmaceutical use thereof. WO2021104413A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HIV-1

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