Anticancer agent 14
Anticancer agent 14 is a lead compound (IC50: 0.20 to 0.65 μM) that induces apoptosis, cell cycle arrest, and loss of mitochondrial membrane potential in breast cancer cells.
Product Specifications
CAS Number
2762698-14-4
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-14.html
Solubility
10 mM in DMSO
Smiles
COC(C=C1)=CC=C1C[C@H]2COC3=CC=CC=C3N2CC4=CC=C(OCCN5CCCC5)C=C4
Molecular Formula
C29H34N2O3
Molecular Weight
458.59
References & Citations
[1]Jana AK, et al. Tyrosine-Derived Novel Benzoxazine Active in a Rat Syngenic Mammary Tumor Model of Breast Cancer. J Med Chem. 2021 Nov 11;64 (21) :16293-16316.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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