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Deoxythymidine-5'-triphosphate-15N2 (dilithium)

Deoxythymidine-5'-triphosphate-15N2 (dTTP-15N2) dilithium is 15N labeled Deoxythymidine-5'-triphosphate (HY-138615) . Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.

Product Specifications

Product Name Alternative

DTTP-15N2 (dilithium)

UNSPSC

12352005

Target

DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/deoxythymidine-5-triphosphate-15n2-dilithium.html

Concentration

100 mM in 20.16 μL Tris HCl/H2O buffer pH=7.5

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O=C([15N]1[C@H]2C[C@H](O)[C@@H](COP(O)(OP(OP(O)(O[Li])=O)(O[Li])=O)=O)O2)[15NH]C(C(C)=C1)=O

Molecular Formula

C10H15Li2 15N2O14P3

Molecular Weight

496.02

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Tattersall MH, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975;5 (2) :191-202.

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Curated Selection

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