Quinacrine (hydrochloride hydrate)
Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine hydrochloride hydrate suppresses NF-κB and activates p53 signaling, which results in the induction of the apoptosis[1].
Product Specifications
CAS Number
6151-30-0
Product Name Alternative
Mepacrine (hydrochloride hydrate) ; SN-390 (hydrochloride hydrate)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; Mitophagy; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/quinacrine-hydrochloride-hydrate.html
Purity
98.18
Solubility
10 mM in DMSO
Smiles
CC(NC1=C(C=C(OC)C=C2)C2=NC3=CC(Cl)=CC=C31)CCCN(CC)CC.[H]Cl.[H]Cl.[H]O[H].[H]O[H]
Molecular Formula
C23H36Cl3N3O3
Molecular Weight
508.91
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
Plasmodium
Frequently Asked Questions
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