6-Maleimidocaproic acid sulfo-NHS
6-Maleimidocaproic acid sulfo-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[103848-61-9]
Product Name Alternative
Sulfo-EMCS (free acid)
UNSPSC
12352005
Hazard Statement
H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6-maleimidocaproic-acid-sulfo-nhs.html
Solubility
10 mM in DMSO
Smiles
O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCCCN2C(C=CC2=O)=O
Molecular Formula
C14H16N2O9S
Molecular Weight
388.35
Precautions
P261-P264-P271-P280-P304+P340-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Curated Selection
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