Boc-Gln-Ala-Arg-AMC (hydrochloride)
Product Specifications
UNSPSC Description
Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC hydrochloride can also be used for measuring the proteolytic activity of TMPRSS2[1][2].
Target Antigen
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/boc-gln-ala-arg-amc-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](CCC(N)=O)NC(OC(C)(C)C)=O)=O)=O)=O)C=C1O2)=CC2=O.Cl
Molecular Weight
667.15
References & Citations
[1]Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20(2):288-292.|[2]Ko CJ, et al. Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis. Oncogene. 2020 Sep;39(37):5950-5963.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-134432A/Boc-Gln-Ala-Arg-AMC-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-134432A/
Clinical Information
No Development Reported
CAS Number
201849-55-0
Curated Selection
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