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ERK-IN-2 (free base)

ERK-IN-2 free base is a ERK2 inhibitor with an IC50 value of 1.8 nM. ERK-IN-2 free base might lead to off-target toxicity and/or off-target activity at dose >10 μM[1].

Product Specifications

CAS Number

2743576-55-6

UNSPSC

12352005

Target

ERK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/erk-in-2-free-base.html

Solubility

10 mM in DMSO

Smiles

OCC1=C2C(NN=C2)=CC(NC(N[C@@H](C3=CC=CC=C3)C)=O)=N1

Molecular Formula

C16H17N5O2

Molecular Weight

311.34

References & Citations

[1]MRK-ERK Inhibitor and Negative Control.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ERK2

Frequently Asked Questions

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