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Pyracrenic acid

Pyracrenic acid is an elastase inhibitor (IC50 = 2.42 µM), can be obtained from the bark of Pyracantha crenulata. Pyracrenic acid has DPPH free radical scavenging activity and anti-inflammatory activity[1][2].

Product Specifications

CAS Number

80832-44-6

UNSPSC

12352005

Target

Elastase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pyracrenic-acid.html

Solubility

10 mM in DMSO

Smiles

CC1(C)[C@@H](OC(/C=C/C2=CC=C(O)C(O)=C2)=O)CC[C@]3(C)[C@@]4([H])CC[C@]5([H])[C@@]6([H])[C@H](C(C)=C)CC[C@@](C(O)=O)6CC[C@](C)5[C@@](C)4CC[C@@]13[H]

Molecular Formula

C39H54O6

Molecular Weight

618.84

References & Citations

[1]Otsuka H, et al. Studies on anti-inflammatory agents. V. A new anti-inflammatory constituent of Pyracantha crenulata roem. Chem Pharm Bull (Tokyo) . 1981 Nov;29 (11) :3099-104. |[2]Kim J H, et al. Compounds with elastase inhibition and free radical scavenging activities from Callistemon lanceolatus. J Med Plants Res. 2009, 3 (11) : 914-920.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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