m-PEG5-succinimidyl carbonate
Product Specifications
UNSPSC Description
m-PEG5-succinimidyl carbonate is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG5-succinimidyl carbonate is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
Target Antigen
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/m-peg5-succinimidyl-carbonate.html
Solubility
10 mM in DMSO
Smiles
COCCOCCOCCOCCOCCOC(ON1C(CCC1=O)=O)=O
Molecular Weight
393.39
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-130150/m-PEG5-succinimidyl-carbonate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-130150/
Clinical Information
No Development Reported
CAS Number
1058691-00-1
Curated Selection
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