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Nicotinoyl azide

Nicotinoyl azide is capable of forming high energy intermediates known to form C-8 adducts with adenosine and guanosine[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Product Specifications

CAS Number

[4013-72-3]

UNSPSC

12352005

Hazard Statement

H301, H311, H331, H372

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/nicotinoyl-azide.html

Purity

99.91

Solubility

DMSO : 10 mg/mL (ultrasonic)

Smiles

O=C(N=[N+]=[N-])C1=CC=CN=C1

Molecular Formula

C6H4N4O

Molecular Weight

148.12

Precautions

H301, H311, H331, H372

References & Citations

[1]Chao Feng, et al. Light-activated chemical probing of nucleobase solvent accessibility inside cells. Nat Chem Biol. 2018 Mar;14 (3) :276-283.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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