Nicotinoyl azide
Nicotinoyl azide is capable of forming high energy intermediates known to form C-8 adducts with adenosine and guanosine[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[4013-72-3]
UNSPSC
12352005
Hazard Statement
H301, H311, H331, H372
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/nicotinoyl-azide.html
Purity
99.91
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O=C(N=[N+]=[N-])C1=CC=CN=C1
Molecular Formula
C6H4N4O
Molecular Weight
148.12
Precautions
H301, H311, H331, H372
References & Citations
[1]Chao Feng, et al. Light-activated chemical probing of nucleobase solvent accessibility inside cells. Nat Chem Biol. 2018 Mar;14 (3) :276-283.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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