Bis-ANS (dipotassium)
Bis-ANS dipotassium is a fluorescent probe of hydrophobic protein. Bis-ANS binds to tubulin with a Kd of 2 μM[1]. Bis-ANS dipotassium is a potent biphasic modulator of protein liquid-liquid phase separation (LLPS) . Bis-ANS dipotassium promotes LLPS at low concentrations but suppresses LLPS at high concentrations[2].
Product Specifications
CAS Number
65664-81-5
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Microtubule/Tubulin
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bis-ans-dipotassium.html
Purity
99.0
Solubility
DMSO : 30 mg/mL (ultrasonic; warming)
Smiles
O=S(C1=CC=CC2=C(C3=C4C=CC=C(S(=O)(O[K])=O)C4=C(NC5=CC=CC=C5)C=C3)C=CC(NC6=CC=CC=C6)=C12)(O[K])=O
Molecular Formula
C32H22K2N2O6S2
Molecular Weight
672.85
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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