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Cytidine-5'-triphosphate-13C9 (dilithium)

Cytidine-5'-triphosphate-13C9 (Cytidine triphosphate-13C9 dilithium; 5'-CTP-13C9) dilithium is 13C-labeled Cytidine-5'-triphosphate (HY-125818) . Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP) . Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii.

Product Specifications

Product Name Alternative

Cytidine triphosphate-13C9 (dilithium) ; 5'-CTP-13C9 (dilithium)

UNSPSC

12352005

Target

DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Applications

COVID-19-anti-virus

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cytidine-5-triphosphate-13c9-dilithium.html

Concentration

100 mM in 19.84 μL Tris HCl/H2O buffer pH=7.5

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O[13C@H]1[13C@@H](O)[13C@H](N2[13C](N=[13C](N)[13CH]=[13CH]2)=O)O[13C@@H]1[13CH2]OP(OP(OP(O)(O[Li])=O)(O[Li])=O)(O)=O

Molecular Formula

13C9H14Li2N3O14P3

Molecular Weight

503.96

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Heidy Y Narvaez-Ortiz, et al. A CTP Synthase Undergoing Stage-Specific Spatial Expression Is Essential for the Survival of the Intracellular Parasite Toxoplasma gondii. Front Cell Infect Microbiol. 2018 Mar 22;8:83.

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Curated Selection

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