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Vitamin D binding protein antibody

Product Specifications

Background

Vitamin D binding protein is a sparsely glycosylated serum protein responsible for highly specific binding and tissue-specific delivery of vitamin D and its metabolites. In addition, it is also an actin scavenger, and is the precursor to the immunomodulatory protein, Gc-MAF. Vitamin D binding protein has been proposed to have significant roles in C5a chemotaxis, osteoclast development and possibly in macrophage activation/recruitment.

Synonyms

Vitamin D-binding protein (DBP, VDB) |Gc protein-derived macrophage activating factor (Gc-MAF, GcMAF) |Gc-globulin|Group-specific component (Gc) |Vitamin D-binding protein-macrophage activating factor (DBP-maf) |GC

Gene ID

2638

UniProt

P02774

Host

Mouse

Reactivity

Human

Immunogen

Group-specific component (vitamin D binding protein)

Target

Vitamin D binding protein

Clonality

Monoclonal

Isotype

IgG1

Applications

ELISA, WB

Field of Research

Metabolism

Purification

Protein A+G purification

Dilution

WB: 1:1000-1:10000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

53 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

2H10

Tested Applications

ELISA, WB

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