Pyrindamycin A
Pyrindamycin A is an antibiotic that inhibits DNA synthesis. Pyrindamycin A shows antitumor activities against murine leukemia, exhibits stronger cytotoxic activities towards murine and human tumor cell lines and especially towards doxorubicin-resistant cells, inhibits P388 and P388/ADR cells with the same IC50 of 3.9 μg/ml[1].
Product Specifications
CAS Number
[118292-36-7]
UNSPSC
12352005
Target
Antibiotic; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/pyrindamycin-a.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@](NC1=C(O)C=C2N(C(C(N3)=CC4=C3C(OC)=C(OC)C(OC)=C4)=O)C[C@@H](CCl)C2=C15)(C)C5=O)OC
Molecular Formula
C26H26ClN3O8
Molecular Weight
543.95
References & Citations
[1]Ishii S, et al. Antitumor activity of pyrindamycins A and B. J Antibiot (Tokyo) . 1989 Nov;42 (11) :1713-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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