(S)-JNJ-54166060
Product Specifications
UNSPSC Description
(S)-JNJ-54166060 is an enantiomer of JNJ 54166060. JNJ 54166060 is a potent P2X7 antagonist[1].
Target Antigen
P2X Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-jnj-54166060.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC(C(F)(F)F)=C1Cl)N2CCC3=C(N=CN3C4=NC=C(F)C=C4)[C@@H]2C
Molecular Weight
438.81
References & Citations
[1]Swanson DM, et al. Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor. J Med Chem. 2016;59(18):8535-8548.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124300A/S-JNJ-54166060-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124300A/
Clinical Information
No Development Reported
CAS Number
1627900-42-8
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