Fluindione
Fluindione is a inhibitor of 5-lipoxygenase with the IC50 of 15 μM. Fluindione has antiinflammatory activity[1].
Product Specifications
CAS Number
957-56-2
UNSPSC
12352005
Hazard Statement
H301, H315, H319, H335
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fluindione.html
Solubility
10 mM in DMSO
Smiles
O=C1C(C(C2=C1C=CC=C2)=O)C3=CC=C(C=C3)F
Molecular Formula
C15H9FO2
Molecular Weight
240.23
Precautions
H301, H315, H319, H335
References & Citations
[1]Brooks, et al. Structural analysis of 2-aryl-1,3-dione compounds as inhibitors of 5-lipoxygenase. Bioorganic & Medicinal Chemistry Letters, 2 (10), 1309–1314.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
Phase 4
Frequently Asked Questions
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