14,15-EE-5 (Z) -E
14,15-EE-5 (Z) -E is a structural analogue of 14, 15-epoxide dicartrienoic acid (14,15-EET) . 14,15-EE-5 (Z) -E antagonizes the relaxation of vascular smooth muscle induced by EET[1].
Product Specifications
CAS Number
[519038-92-7]
UNSPSC
12352005
Hazard Statement
H225, H319
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/14-15-ee-5-z-e.html
Concentration
308.17 μM * 250 μL in Ethanol
Purity
99.9
Solubility
10 mM in DMSO
Smiles
OC(CCC/C=C\CCCCCCC[C@@H]1[C@@H](O1)CCCCC)=O
Molecular Formula
C20H36O3
Molecular Weight
324.50
Precautions
H225, H319
References & Citations
[1]Gauthier KM, et al. 14,15-epoxyeicosa-5 (Z) -enoic-mSI: a 14,15- and 5,6-EET antagonist in bovine coronary arteries. Hypertension. 2003 Oct;42 (4) :555-61.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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