RS-5773

RS-5773 is a calcium channel inhibitor and a diltiazem congener. RS-5773 has antianginal effect and does not cause excessive hypotension or depression of atrioventricular conduction [1].

Product Specifications

CAS Number

129173-57-5

UNSPSC

12352005

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/rs-5773.html

Solubility

10 mM in DMSO

Smiles

O=C1[C@@H]([C@@H](SC2=CC(CC3=CC=CS3)=CC=C2N1CCN(C)C)C4=CC=C(C=C4)OC)OC(C)=O.[H]Cl

Molecular Formula

C27H31ClN2O4S2

Molecular Weight

547.13

References & Citations

[1]H Shiga, et al. Antianginal effect of RS-5773, a diltiazem congener, in the methacholine-induced anginal model in rats. Jpn J Pharmacol . 1996 Dec;72 (4) :365-74.