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Sorbitan trioleate

Sorbitan trioleate is an orally active nonionic surfactant with low toxicity (LD≥200 mg/kg) . Sorbitan trioleate can be used as an excipient, such as surfactant, emulsifier, lubricant, wetting agent, dispersant, thickener, defoamer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

Product Specifications

CAS Number

[26266-58-0]

Product Name Alternative

Span 85

UNSPSC

12352200

Hazard Statement

H315, H319

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sorbitan-trioleate.html

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

CCCCCCCC/C=C\CCCCCCCC(OC[C@@H](O)[C@@H]1[C@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)[C@@H](OC(CCCCCCC/C=C\CCCCCCCC)=O)CO1)=O

Precautions

H315, H319

References & Citations

[1]YAMAMOTO H, et al. Study on subacute toxicity of intravenous sorbitan trioleate (STO) in Wistar rats[J]. The Journal of Toxicological Sciences, 1983, 8 (4) : 301-310.|[2]Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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