MHY908
MHY908 is a potent dual agonist of PPARα and PPARγ[1]. MHY908 also inhibits melanogenesis through inhibition of mushroom tyrosinase activity[2].
Product Specifications
CAS Number
1393371-39-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mhy908.html
Solubility
10 mM in DMSO
Smiles
CC(OC1=CC=C(C=C1)C2=NC3=CC(Cl)=CC=C3S2)(C(O)=O)C
Molecular Formula
C17H14ClNO3S
Molecular Weight
347.82
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Park MH, et al. Potent anti-diabetic effects of MHY908, a newly synthesized PPAR α/γ dual agonist in db/db mice. PLoS One. 2013 Nov 14;8 (11) :e78815. |[2]Park MH, et al. Inhibition of melanogenesis by 2-[4- (5-chlorobenzo[d]thiazol-2-yl) phenoxy]-2-methylpropanoic acid (MHY908) . Arch Pharm Res. 2015 Apr;38 (4) :505-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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