D-Fructose-6-phosphate

D-Fructose 6-phosphate is an endogenous metabolite in saliva that affects cell growth and autophagy; it can be hydrolyzed by Fructose-1,6-bisphosphatase (FBPase) . D-Fructose-6-phosphate can be converted into D-glucose 6-phosphate (HY-112537) by the action of phosphoglucose isomerase. D-Fructose-6-phosphate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose 6-phosphate can be used to study Lewy body dementia[1][2].

Product Specifications

CAS Number

[643-13-0]

UNSPSC

12352211

Hazard Statement

H302, H315, H319

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/D-Fructose_6-phosphate.html

Purity

99.90

Solubility

10 mM in DMSO

Smiles

OCC([C@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)=O

Molecular Formula

C6H13O9P

Molecular Weight

260.14

Precautions

H302, H315, H319

References & Citations

[1]Tsuruoka M, et al. Capillary electrophoresis-mass spectrometry-based metabolome analysis of serum and saliva from neurodegenerative dementia patients. Electrophoresis. 2013 Oct;34 (19) :2865-72.|[2]Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39 (35) :5709-5720. |[3]Hardie DG, et al. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol. 2012 Mar 22;13 (4) :251-62.