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Isoxepac-d6

Isoxepac-d6 (HP 549-d6) is the deuterium labeled Isoxepac (HY-W050088) . Isoxepac (HP 549) is an orally active non-steroidal anti-inflammatory agent. Isoxepac can inhibit Carrageenan (HY-125474) paw oedema, adjuvant-induced polyarthritis, and prostaglandin synthesis. Isoxepac (200 mg) has an analgesic effect after meniscectomy with a low incidence of side effects. Isoxepac can be used in the research of inflammatory (rheumatoid arthritis) and pain-related diseases[1].

Product Specifications

CAS Number

[2012598-71-7]

Product Name Alternative

HP 549-d6

UNSPSC

12352005

Target

Drug Derivative; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Inflammation/Immunology; Neurological Disease

Solubility

10 mM in DMSO

Smiles

O=C1C2=CC(CC(O)=O)=CC=C2OC([2H])([2H])C3=C([2H])C([2H])=C([2H])C([2H])=C31

Molecular Formula

C16H6D6O4

Molecular Weight

274.30

References & Citations

[1]Illing HP, et al. Species differences in the disposition and metabolism of 6,11-dihydro-11-oxodibenz[be]oxepin-2-acetic acid (isoxepac) in rat, rabbit, dog, rhesus monkey, and man. Drug Metab Dispos. 1978 Sep-Oct;6 (5) :510-7.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Curated Selection

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