SIRT1 activator 3

SIRT1 activator 3 is a potent activator of Sirt1 and suppresses TNF-α in a dose-dependent manner. SIRT1 activator 3 has the potential for anti-obesity or anti-diabetic researches[1].

Product Specifications

CAS Number

[839699-72-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Sirtuin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sirt1-activator-3.html

Purity

99.9

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(N)N(CCCOC)C2=NC3=CC=CC=C3N=C21)NC4CCCC4

Molecular Formula

C20H25N5O2

Molecular Weight

367.44

Precautions

H302, H315, H319, H335

References & Citations

[1]Nayagam VM, et al. SIRT1 modulating compounds from high-throughput screening as anti-inflammatory and insulin-sensitizing agents. J Biomol Screen. 2006 Dec;11 (8) :959-67.