Glutamine Synthetase (GLUL) Mouse Monoclonal Antibody [Clone ID: LBI2C12]

Product Specifications

Background

The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Overview

Carrier-free (BSA/glycerol-free) GS mouse monoclonal antibody, clone LBI2C12

Synonyms

GLNS; GS; PIG43; PIG59

Gene Name

Homo sapiens glutamate-ammonia ligase (GLUL), transcript variant 3, mRNA.

Gene ID

2752

UniProt

P15104

Conjugation

Unconjugated

Related Pathways

Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways, Nitrogen metabolism

Field of Research

Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways, Nitrogen metabolism

Dilution

IHC 1:700

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.