HIV-1 inhibitor-61
HIV-1 inhibitor-61 (2c) is a HIV-1 reverse transcriptase inhibitor, with an EC50 of 0.07 nM in NL4-3 wt MT-4 cells[1].
Product Specifications
CAS Number
[1114507-62-8]
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-61.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(SC[C@H]2[C@H](C3=CC=C(OC)C=C3)C2)=NC([C@@H](C4=C(F)C=CC=C4F)C)=C1C
Molecular Formula
C24H24F2N2O2S
Molecular Weight
442.52
References & Citations
[1]Marco Radi, et al. Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants. J Med Chem. 2009 Feb 12;52 (3) :840-51.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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