Oleoylethanolamide-d2

Oleoylethanolamide-d2 is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

Product Specifications

CAS Number

[1245477-09-1]

Product Name Alternative

N-Oleoylethanolamide-d2; Oleamide MEA-d2; Oleic acid monoethanolamide-d2

UNSPSC

12352211

Target

Endogenous Metabolite; Isotope-Labeled Compounds; PPAR

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Metabolic Disease; Cardiovascular Disease

Concentration

3.05 mM * 500 μL in Ethanol

Purity

98.0

Solubility

10 mM in DMSO

Smiles

CCCCCCCC([2H])([2H])/C=C\CCCCCCCC(NCCO)=O

Molecular Formula

C20H37D2NO2

Molecular Weight

327.54

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Chen L, et al. Oleoylethanolamide, an endogenous PPAR-α ligand, attenuates liver fibrosis targeting hepatic stellate cells. Oncotarget. 2015 Dec 15;6 (40) :42530-40