Lirequinil
Lirequinil (Ro 41-3696) is an orally active partial agonist of the benzodiazepine (BDZ) receptor. Lirequinil has the effect of promoting sleep[1].
Product Specifications
CAS Number
[143943-73-1]
Product Name Alternative
Ro 41-3696
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lirequinil.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C[C@@H](OCC)CC1)C2=C3C4=C(C=CC(Cl)=C4)CCN3C(C(C5=CC=CC=C5)=C2)=O
Molecular Formula
C26H25ClN2O3
Molecular Weight
448.94
References & Citations
[1]M Tsuboi, et al. Changes in mouse hippocampal EEG characteristics after oral administration of Ro 41-3696, nitrazepam, or zopiclone alone and in combination with ethanol. Pharmacology. 1994 Nov;49 (5) :278-85.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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