Panadiplon

Panadiplon (FG 10571; PNU 78875), a benzodiazepine receptor, is a 5GABAA partial agonist. Panadiplon exhibits selectivity for 5GABAA receptors versus 1GABAA receptors[1].

Product Specifications

CAS Number

124423-84-3

Product Name Alternative

FG 10571; PNU 78875

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/panadiplon.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(C3=NOC(C4CC4)=N3)N=CN2C5=C(N1C(C)C)C=CC=C5

Molecular Formula

C18H17N5O2

Molecular Weight

335.36

References & Citations

[1]Platt DM, et al. Contribution of alpha 1GABAA and alpha 5GABAA receptor subtypes to the discriminative stimulus effects of ethanol in squirrel monkeys. J Pharmacol Exp Ther. 2005 May;313 (2) :658-67.