Vapendavir

Vapendavir (BTA798) is a potent enteroviral capsid binder (CB) . Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].

Product Specifications

CAS Number

[439085-51-5]

Product Name Alternative

BTA798

UNSPSC

12352005

Target

Enterovirus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/vapendavir.html

Solubility

10 mM in DMSO

Smiles

CCOC1=NOC2=CC(OCCC3CCN(C4=CC=C(C)N=N4)CC3)=CC=C12

Molecular Formula

C21H26N4O3

Molecular Weight

382.46

References & Citations

[1]Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58 (11) :6990-2.|[2]Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59 (12) :7782-5.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Citation 01

ACS Infect Dis. 2020 May 8;6 (5) :882-890.|SSRN. 2024 Apr 19.|Eur J Med Chem. 2025 Feb 14:288:117395.|Norwegian University of Science and Technology. 2023 May.