Arofylline
Arofylline is a PDE4 inhibitor as a potential research for asthma.
Product Specifications
CAS Number
[136145-07-8]
Product Name Alternative
LAS 31025
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/arofylline.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC)N(C2=CC=C(Cl)C=C2)C3=C(N=CN3)C1=O
Molecular Formula
C14H13ClN4O2
Molecular Weight
304.73
References & Citations
[1]Chorostowska-Wynimko J, Kus J, Skopińska-Rózewska E. Theophylline inhibits free oxygen radicals production by human monocytes via phosphodiesterase inhibition. J Physiol Pharmacol. 2007;58 Suppl 5 (Pt 1) :95-103.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
PDE4
Curated Selection
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