CaVα2δ1 rabbit pAb
Calcium voltage-gated channel auxiliary subunit alpha2delta 1 (CACNA2D1) Homo sapiens The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014],
Product Specifications
Background
Synonyms
Gene ID
781
UniProt
P54289
Cellular Locus
Membrane ; Single-pass type I membrane protein.
Host
Rabbit
Species Reactivity
Rat
Reactivity
Rat
Immunogen
Synthetic Peptide of CaVα2δ1
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF
Validated Applications
WB,IHC,IF
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
100-130kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES20793-1.pdf
Observed Molecular Weight
100 - 130 kD
Subcellular Location
Membrane ; Single-pass type I membrane protein .
Other Product Names
Gene ID (Human)
781
SwissProt (Human)
P54289
Available Sizes
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