CaVα2δ1 rabbit pAb

Calcium voltage-gated channel auxiliary subunit alpha2delta 1 (CACNA2D1) Homo sapiens The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014],

Product Specifications

Background

UniProt

P54289

Swiss Prot

P54289

Reactivity

Rat

Immunogen

Synthetic Peptide of CaVα2δ1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight

100-130kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

100-130kD

Fragment

IgG

Subcellular Location

Membrane ; Single-pass type I membrane protein .

Other Product Names

Voltage-dependent calcium channel subunit alpha-2/delta-1 (Voltage-gated calcium channel subunit alpha-2/delta-1) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-1; Voltage-dependent calcium channel subunit delta-1]