Tenascin Antibody / TNC
In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of as Tenascin or Tenascin C. Tenascin C is a multifunctional, disulfide-linked hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 2-4 µg/mL for 30 minutes at RT
UniProt
P24821
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human full-length protein was used as the immunogen for the Tenascin C antibody.
Clonality
Monoclonal
Isotype
IgG2c κ
Clone
TNC/4805
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the Tenascin C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Tenascin C antibody is available for research use only.
Storage Conditions
Aliquot the Tenascin C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the Tenascin C antibody should be determined by the researcher.
Location
Connective tissue matrix
Image Legend
Frequently Asked Questions
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