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Z-JIB-04 (NSC 693627)

Product Specifications

CAS Number

199596-24-2

Synonyms

JIB-04 Z-isomer, (Z) -JIB-04

Target

Histone Demethylase

Applications

Epigenetics

Smiles

C1=CC=C (C=C1) C (=NNC2=NC=C (C=C2) Cl) C3=CC=CC=N3

Molecular Formula

C17H13ClN4

Additionnal Information

Z-JIB-04 (NSC 693627, JIB-04 Z-isomer) is an isomer of JIB-04. JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC50 of 230 nM, 340 nM, 855 nM, 445 nM, 435 nM, 1100 nM and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively.

Storage Conditions

3 years -20°C powder

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